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DeCS
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Descriptor English:
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Leukoencephalopathy, Progressive Multifocal
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Descriptor Spanish:
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Leucoencefalopatía Multifocal Progresiva
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Descriptor Portuguese:
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Leucoencefalopatia Multifocal Progressiva
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Synonyms English:
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Encephalitis, JC Polyomavirus
Encephalopathies, JC Polyomavirus
Encephalopathy, JC Polyomavirus
JC Polyomavirus Encephalitis
JC Polyomavirus Encephalopathy
Leukoencephalopathies, Progressive Multifocal
Multifocal Leukoencephalopathies, Progressive
Multifocal Leukoencephalopathy, Progressive
Progressive Multifocal Leukoencephalopathies
Progressive Multifocal Leukoencephalopathy
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Tree Number:
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C01.207.245.340.500
C01.207.399.750.500
C01.925.182.525.500
C01.925.256.721.500
C01.925.839.550
C10.228.140.430.520.750.500
C10.228.140.695.750
C10.228.228.245.340.500
C10.228.228.399.750.500
C10.314.450
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Definition English:
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An opportunistic viral infection of the central nervous system associated with conditions that impair cell-mediated immunity (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME and other IMMUNOLOGIC DEFICIENCY SYNDROMES; HEMATOLOGIC NEOPLASMS; IMMUNOSUPPRESSION; and COLLAGEN DISEASES). The causative organism is JC Polyomavirus (JC VIRUS) which primarily affects oligodendrocytes, resulting in multiple areas of demyelination. Clinical manifestations include DEMENTIA; ATAXIA; visual disturbances; and other focal neurologic deficits, generally progressing to a vegetative state within 6 months. (From Joynt, Clinical Neurology, 1996, Ch26, pp36-7) |
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History Note English:
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1973(1971)
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Allowable Qualifiers English:
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Record Number:
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29437
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Unique Identifier:
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D007968
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Occurrence in VHL:
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Similar:
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DeCS
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